婴儿猝死，原因何在？

choi

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VOA Chinese, Feb. 22,2 010.
http://www1.voanews.com/chinese/news/US/20100222_HEALTHSIDSUPDATE-84990262.html

My comment:
(a) 波士顿儿童医院 Children's Hospital, Boston: one of teaching hospitals of
Harvard Medical School.
(b) 汉纳·金尼 Hannah Kinney, MD
http://www.childrenshospital.org/cfapps/research/data_admin/Site164/mainpageS164P0.html

Note: Kinney is abbreviated from "McKinney."

(c) Abstract of the publication:

Duncan JR, Paterson DS, Hoffman JM, Mokler DJ, Borenstein NS, Belliveau RA,
Krous HF, Haas EA, Stanley C, Nattie EE, Trachtenberg FL, and Kinney HC,
Brainstem serotonergic deficiency in sudden infant death syndrome. JAMA, 303
:430-7 (Feb 3, 2010).
http://www.ncbi.nlm.nih.gov/pubmed/20124538
("CONCLUSION: Compared with controls, SIDS was associated with lower 5-HT
and TPH2 levels, consistent with a disorder of medullary 5-HT deficiency")

(i) sudden infant death syndrome (SIDS)
(ii) 羟色胺 serotonin, also known as 5-hydroxytryptamine (5-HT).
(iii) Its key biosynthetic enzyme is tryptophan hydroxylase (TPH2).

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