Male Infertility Among Chinese Men

choi

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Pam Belluck, Study Links Male Infertility to a Missing Protein; A mutation may be a hurdle to conception, with a sperm viewed as an invader. New York Times, July 21, 2011.
http://www.nytimes.com/2011/07/21/us/21fertility.html?scp=1&sq=infertility%20china&st=cse

(a) Quote:

"Men with two copies of the defective gene do not produce the protein.

"besides the 25 percent of men with two mutated copies, half of men have one mutated and one normal copy with no effect on fertility

(b) Note:
(i) The report cites
Tollner TL et al, A Common Mutation in the Defensin DEFB126 Causes Impaired Sperm Function and Subfertility. Science transational medicine, 3: _-_ (July 20, 2011).
http://stm.sciencemag.org/content/3/92/92ra65.abstract?sid=c44f8dba-ffd5-44db-a15d-7021a7351dee
(ii) "Beta-defensin 126 is a protein that in humans is encoded by the DEFB126 gene"
http://en.wikipedia.org/wiki/DEFB126

DEFB126. Gene Symbol reort, Hugo Gene Nomenclature Committee (HGNC), undated.
http://www.genenames.org/data/hgnc_data.php?hgnc_id=15900

It appears that DEFB is just the acronym for DEFensin Beta.


----------------------------------separately
Felicity Barringer, To Nullify Lead, Add a Bunch of Fish Bones; New strategy, cheaper than carting off topsoil, helps ease toxic waste. New York Times, July 21, 2011.
http://www.nytimes.com/2011/07/21/science/earth/21fishbones.html?scp=1&sq=lead%20fish&st=cse

(a) Excerpt in the wondow of print: An alchemy creates a crystalline mineral that is not harmful.

(b) Quote: "The principle is straightforward, said Victor R. Johnson, an engineer with Civil & Environmental Consultants Inc. “The fish bones are full of calcium phosphate,” he said. “As they degrade, the phosphates migrate into the soil.” The lead in the soil, deposited by car exhaust from the decades when gasoline contained lead or from lead-based paint residue, binds with the phosphate and transforms into pyromorphite, a crystalline mineral that will not harm anyone even if consumed.

(c) Note: pyromorphite
http://en.wikipedia.org/wiki/Pyromorphite
(a mineral species composed of lead chlorophosphate: Pb5(PO4)3Cl)

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