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Henoch–Schönlein purpura

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发表于 7-14-2017 12:05:36 | 只看该作者 回帖奖励 |倒序浏览 |阅读模式
Lisa Sanders, 'Dad, I Can't Walk.'  The rash formed rings around a young boy's ankle, and his joints hurt. Was it an allergy?  New York Times Magazine, July 9, 2017.
https://www.nytimes.com/2017/07/ ... young-boy-walk.html

Note:
(a) "He and his wife considered the possibility of chickenpox, but the child had received the varicella vaccine. * * * He'd [The boy had] also complained about pain in his ankle and another time in his knee. * * * Neither joint [gad] looked red or swollen * * * The father hurried over to the boy. An irregular band of solid red ringed both legs, just above the anklebone.  The boundary between rash and normal skin was well defined and jagged * * * The ankles might have been a little swollen. * * * They [red dots in the rash] were itchy at first but now were kind of sore. * * * no fever * * * The doctor felt one slightly enlarged lymph node on the right side of the boy's neck."
(i) varicella (n; etymology)
https://www.merriam-webster.com/dictionary/varicella
is the medical term for chickenpox.
(ii) talus bone
https://en.wikipedia.org/wiki/Talus_bone
(also known as angle bone, is [the largest] one of the group of foot bones known as the tarsus [Latin for ankle] )
(A) Click "tarsus" and you will see one can not feel talus through the skin.
(B) Ankle joint is formed between the two bones (medical terms: tibia and fibula) in the legs AND talus (altogether three bones).  

(b) "across the boy's buttocks [which is a medical term, corresponding to 'bum' in the slang], were dozens of the same red spots seen on his legs. But here the spots were larger and much darker. And as with the lesions on the boy's legs and ankles, pressure didn't make the rash blanch — an indication that the dots were actually tiny pools of blood deposited within the layers of the skin, a kind of rash known as purpura [accent on the first syllable; Latin noun feminine for the color purple]."

Purpura
https://en.wikipedia.org/wiki/Purpura
("They measure 0.3–1 cm (3–10 mm), whereas petechiae measure less than 3 mm, and ecchymoses [whose singular form is 'ecchymosis'] greater than 1 cm")
(c) "The doctor thought the child had something more common and benign: an autoimmune disorder known as Henoch-Schönlein purpura (HSP). This disease, first described more than 200 years ago, usually affects children under 12 and is characterized by migrating joint pain and a purpuric rash that is worse in areas of pressure. That would explain the ankle rash — probably a result of pressure from the child’s snow boots — and the lesions on his buttocks. There is no test for this disorder, so the diagnosis is made based on the history and exam."

Henoch–Schönlein purpura
https://en.wikipedia.org/wiki/Henoch–Schönlein_purpura
("HSP is often preceded by an infection, such as a throat infection.  HSP is a systemic vasculitis (inflammation of blood vessels) and is characterized by deposition of immune complexes containing the antibody immunoglobulin A (IgA); the exact cause for this phenomenon is unknown. * * * is named after Eduard Heinrich Henoch (1820–1910), a German pediatrician * * * and his teacher Johann Lukas Schönlein (1793–1864), who described it in the 1860s")

The English pronunciation for "ch" (in Henoch) is "k" and and "ei" (in Schönlein) sounds like "eye" in English.

(d) Dr Wolffe Nadoolman "died suddenly in April"
(i) Obituary. East Bay Times, May 6, 2017
http://www.legacy.com/obituaries ... .aspx?pid=185294630
("1957 - 2017 Emeryville[, California, where he lived] Wolffe Jay Nadoolman MBA, MD, beloved pediatrician in Berkeley, CA died peacefully in his sleep on Friday, April 28. He was 60 years old.  Wolffe grew up in Washington Heights [around Columbia medical school, in Manhattan], NYC * * * [as an undergraduate] attended Cornell University where he graduated with a triple major in Astrophysics, Math and Art History. Wolffe continued his education at Harvard Business School, graduating in 1981. He worked for a number of investment banking firms, settling on Salomon Brothers where he was promoted to Vice President in Charge of Options and Mortgage Securities Trading. His departure from the firm was rendered in dramatic detail in Michael Lewis' memoir of Wall Street, Liar's Poker. Wolffe joked that, 'names were changed to protect the innocent.' Starting a completely new career and path for life, Wolffe went on to fulfill a lifelong dream to become a pediatrician and to care for children. He received his MD from the Yale School of Medicine in 1996")
(A) Michael Lewis, Liar's Poker; Rising through the wreckage on Wall Street. Norton, 1989.
(B) Liar's Poker
https://en.wikipedia.org/wiki/Liar%27s_Poker
(ii) Emeryville, California
https://en.wikipedia.org/wiki/Emeryville,_California

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